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Building Block
Phase transfer catalyst
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Cis-4-hydroxy-D-proline
N-BOC-4-Oxo-L-Proline
N-Boc-cis-4-hydroxy-L-proline
N-Boc-trans-4-hydroxy-L-proline
N-Boc-trans-4-hydroxy-L-proline methyl ester
N-Boc-cis-4-hydroxy-L-proline methyl ester
N-Boc-Cis-4-Hydroxy-D-proline methyl ester
N-Boc-Trans-4-Hydroxy-D-proline methyl ester
N-Boc-Tran-4-Fluoro-L-proline
N-Boc-Cis-4-Fluoro-L-proline
N-Boc-Tran-4-Fluoro-D-proline
N-Boc-Cis-4-Fluoro-D-proline
N-Boc-Trans-4-Amino-L-proline methyl ester
N-Boc-Cis-4-Chloro-L-proline methyl ester
Methyl 3-pyrrolidinecarboxylate hydrochloride
N-Boc-3-pyrrolidine carboxylic acid
Methyl 1-Boc-3-pyrrolidinecarboxylate
3-pyrrolidinone hydrochloride
N-Boc-3-pyrrolidinone
p-Acetoxy Styrene
4-tert-butoxystyrene
4-Methoxystyrene
4-(Ethoxyethoxy)styrene
2,4-dimethyl-1H-pyrrole
Pyrrole-2-carboxaldehyde
Pyrrole-3-carboxaldehyde
N-Methylpyrrole-2-carboxaldehyde
5-(Trifluoromethyl)-1H-pyrrole-2-carbaldehyde
3,5-dimethyl-1H-pyrrole-2-carbaldehyde
(S)-1,1,1-Trifluoroisopropylamine hydrochloride
Methoxylamine HCL
(R)-1,1,1-Trifluoroisopropylamine hydrochloride
Tert-Butyl-2,2,2-trichloroacetimidate
NI-(S)-BPB-GLY
benzyl2,2,2-trichloroacetimidate
NI-(R)-BPB-GLY
1-cyclopropylpiperazine
3-Hepten-2-one
tert-butyl (S)-2-ethylpiperazine-1-carboxylate
Cyclobutane-1,2,3,4-tetracarboxylic dianhydride
tert-butyl (S)-3-ethylpiperazine-1-carboxylate
3-Hydroxypiperidine
(2S,5R)-2-ETHYL-5-METHYL-N-BOC-PIPERAZINE
5-Bromo-4,7-diazaindole
3-Oxocyclobutanecarboxylic acid
1H-Benzimidazole-2-ethanamine 2HCL
Cyclopentancarboxylic Acid
2-(1H-Benzo[d]imidazol-2-yl)ethanamine
CyclohexaneMethylaMine
2-(2-Chloroethoxy)acetic acid
1H-Benzimidazole-2-ethanamine 2HCL
6-Chloro-1H-pyrazolo[4,3-c]pyridine
2-(1H-Benzo[d]imidazol-2-yl)ethanamine
((3S,4R)-4-(4-Fluorophenyl)piperidin-3-yl)methanol
ethyl 1H-imidazole-2-carboxylate
2-[2-(2-Propynyloxy)ethoxy]ethylamine
(3-methyl-1,2,4-oxadiazol-5-yl)methanol
2-Amino-5-bromo-3-ethynylpyrazine
2-methyl-3-furoic acid
2-Cyclopropylbenzenemethanamine
4-(1-methylcyclopropyl)butanoic acid
2-Cyclopropylbenzenemethanamine HCL
3-amino-4-ethyl-1H-pyrazole
1,3-Dimethylpyrazole
8-iodo-6-phenylbenzo[d]naphtho[2,1-b]furan
2-bromo-1-phenylpropane
4-fluorobenzofuran-7-carbaldehyde
8-iodo-6-phenylbenzo[d]naphtho[2,1-b]furan
2-amino-5-phenyl-[1,3,4]thiadiazole
Fluoranthene-3-boronic acid
2-bromo-5-phenyl-[1,3,4]thiadiazole
[2-(2-nitrophenyl)thiazolo[5,4-b]pyridin-6-yl]methanol
3-fluoro-4-methyl benzonitrile
5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinoline
2-methyl-4-fluoro benzonitrile
1-Boc-3-bromo-5-nitro-1H-indazole
2-fluoro-5-methyl benzonitrile
3-amino-1H-indazole
2-fluoro-4-cyano Benzyl alcohol
4-chloro-pyrido[2,3-d]pyrimidine
2-bromo-5-fluoro Benzyl alcohol
(2R,3R)-2,3-Bis[(phenylmethoxy)methyl]-oxirane
2-cyano-5-fluoro Benzyl alcohol
3-bromo-4-fluoro Benzyl alcohol
2-fluoro-3-brombo Benzyl alcohol
2-bromo-5-hydroxy benzaldehyde
2-bromo-5-iodobenzoic acid
2-Amino-5-methylbenzoic acid
3-amino-2-hydroxy-N,N-dimethylbenzamide
2,4,5-trifluoro-3-methyl Benzoic acid
3，5-dibromo-2-amino pyrazine
5-hydroxy-6-methyl-2-carboxylic acid pyrazine
methyl 5-chloro-6-methylpyrazine-2-carboxylate
methyl 3-amino-6-bromopyrazine-2-carboxylate
2-Amino-5-bromo-3-ethynylpyrazine
3-Hydroxypiperidine
(S)-1-Boc-3-hydroxypiperidine
(S)-2-(piperidin-2-yl)ethanol
tert-butyl-4-formylpiperidine-1-carboxylate
1-acetyl-piperidie-4-one
((3S,4R)-4-(4-Fluorophenyl)piperidin-3-yl)methanol
4-Chloro-2-aminophenol
3,5-Lutidine
2,6-Lutidine
Cis-Tosylate
O-Benzyl Salbutamol
Cinnamyl alcohol
m-Bromoanisoles
2-(Chloromethyl)-3,4-dimethoxypyridinium hcl
5-Difluormethoxy-2-mercaepto-1H-benzimidazole
(-)-1-[(4-Chlorophenyl)Phenylmethyl] Piperazine
3-(Chloromethyl)-1-methyl-1h-1,2,4-triazole HCL
Methyl 1-methyl-1H-1,2,4-triazole-3-carboxylate
6-Chloro-2-methyl-2H-Indazol-5-amine
3-(Tert-Butyl)-6-(ethylthio)-1,3,5-Triazine-2,4(1H,3H)-dione
((1S,4R)-4-Aminocyclopent-2-en-1-yl)methanol hydrochloride
2-Azabicyclo[2.2.1]hept-5-en-3-one(VINCE LACTAM)
Ethyl 4-[(3-chloro-4-methoxybenzyl)amino]-2-(methylsulfanyl)pyrimidine-5-carboxylate
3-chloro-4-MethoxybenzylaMniehydrochloride
Ethyl (2S,5R)-5-[(benzyloxy)amino]piperidine-2-carboxylate
Ethyl 2-Aminothiazole-4-Carboxylate
1-{2-[4-(chloroMethyl)phenoxy]ethyl}azepane hcl
2-Chloroethyl hexamethylene Imine hydrochloride
(S)-(+)-3-Hydroxytetrahydrofuran
1-(2-pyrimidinyl)piperazine
3,3-tetra methylene glutarimide
2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one，N8
6-(Benzyloxy)-9-((1S,3R,3S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl)-N-((4-methoxyphenyl)diphenylmethyl)-9H-purin-2-amine，N7
(2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol，N5
6-Chloroguanine
Cyclen；1,4,7,10-Tetracyclododecane
Ethyl(3r,4s,5s)-4,5-epoxy-3-(1-ethyl-propoxy)-Cyclohex-1-ene-1-carboxylate
6-Amidino-2-naphthol methanesulfonate
4-(4-Fluorobenzoyl)butyric acid
4-{[(4-Fluorophenyl)imino]methyl}phenol
4-(4-Benzyloxybenzlidipine)-P-Fluoro Aniline
(4S)-3-[5-(4-Fluorophenyl)-1,5-dioxopenyl]-4-phenyl-2-oxazolidinone
(3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-phenylmethoxyphenyl)azetidin-2-one
Ethyl 7-bromo-2,2-dimethylheptanoate
2,2,14,14-Tetramethyl-8-oxopentadecanedioic acid diethyl ester
2-(Chloromethyl)-4-methoxy-3-methylpyridine hydrochloride
5-(1H-Pyrrol-1-yl)-2-mercaptobenzimidazole
(4S)-1-Methyl-2-oxo-Imidazolidine-4-carboxylic acid t-butyl ester
(S)-3-(benzoylthio)-2-methylpropanoicacid
3-Bromo-2,3,4,5-tetrahydro-2H-benzo[b]azepin-2-one
2'-Chloroacetophenone
7-Chloroquinaldine
4-Amino-5-imidazole carboxamide Hcl
[2-(2-nitrophenyl)thiazolo[5,4-b]pyridin-6-yl]methanol
Thiomorpholine dioxide hydrogen
4-Hydroxy-7-phenoxy-3-isoquinolinecarboxylic acid methyl ester
Methyl 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylate
(6bR,10aS)-Ethyl 3-methyl-2,3,6b,7,10,10a-hexahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxaline-8(9H)-carboxylate
(6bR,10aS)-3-Methyl-2,3,6b,7,8,9,10,10a-octahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxaline
Tert-butyl 4-(6-amino-3-pyridyl)piperazine-1-carboxylate
6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one
2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid
2,4-Dichloro-5-methoxyaniline
4-chloro-7-(3-chloropropoxy)-6-methoxyquinoline-3-carbonitrile
7-(3-Chloropropoxy)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methoxyquinoline-3-carbonitrile
1-chloro-5-isopropoxy-2-methyl-4-nitrobenzene
5-Methyl-2-(1-Methylethoxy)-4- (4-piperidinyl)- Benzenamine dihcl
tert-butyl 4-(4-aMino-5-isopropoxy-2-Methylphenyl)piperidine-1-carboxylate
2-(isopropylsulfonyl)aniline
2,5-dichloro-N-(2-(isopropylsulfonyl)phenyl)pyrimidin-4-amine
5-Formyl-2-Furanylboronic Acid
N-[3-Chloro-4-(3-fluorobenzyloxy)-phenyl]-6-iodoquinazolin-4-amine
5-[4-[[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-6-quinazolinyl]-2-Furancarboxaldehyde
Lapatinib base
(R)-2-(2,5-Difluorophenyl)pyrrolidine Hcl
5-chloro-3-nitropyrazolo[1,5-a]pyrimidine
(R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-amine
Larotrectinib base
3-(4-bromophenyl)-piperidine
1H-Indazole-7-carboxylicacid
(3S)-3-(4-Bromophenyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester
4-(4-Methylpiperazin-1-ylmethyl)-3-trifluoromethylaniline
3-Iodo-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]benzamide
3-Ethynyl-4-methylbenzoic acid
3-Bromoimidazo[1,2-b]pyridazine
2,5-dichloro-N-(2-(dimethylphosphoryl)phenyl)pyrimidin-4-amine
2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline
N4-(4-(4-ethylpiperazin-1-yl)phenyl)-N6- Methylpyrimidine-4,6-diamine
2,6-Dichloro-3,5-dimethoxyaniline
4-Isothiocyanato-2-(trifluoroMethyl)benzonitrile
N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl] -2-methylalanine
4-((1-Cyanocyclobutyl)amino)-2-fluoro-N-methylbenzamide
1-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)cyclobutanecarboxylic acid
5-isothiocyanato-3-(trifluoromethyl)picolinonitrile
1-Amino-1-cyclobutanecarboxylic acid hydrochloride
3-Methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)aniline
3-bromo-5-chloro-6-ethylpyrazine-2-carbonitrile
3-bromo-6-ethyl-5-((tetrahydro-2H-pyran-4-yl)amino)pyrazine-2-carbonitrile
1-(3-cyano-4-((dimethylamino)methyleneamin
4-([1,2,4]Triazolo[1,5-a]pyridin-7-yloxy)-3-methylaniline
3-(6-Oxo-1,6-dihydro-3-pyridazinyl)benzonitrile
5-Bromo-2-(3-(chloromethyl)phenyl)pyrimidine
3-(1-(3-(5-bromopyrimidin-2-yl)benzyl)-6-oxo-1,6-dihydropyridazin-3-yl)benzonitrile
Pharmaceutical Intermediate > Anti-Cancer Intermediates
No.
Product Name
CAS No.
Structure
USE
1
Tert-butyl 4-(6-amino-3-pyridyl)piperazine-1-carboxylate
571188-59-5
Palbociclib
2
6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one
1016636-76-2
Palbociclib
3
2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid
1211443-58-1
Ribociclib
4
2,4-Dichloro-5-methoxyaniline
98446-49-2
Bosutinib
5
4-chloro-7-(3-chloropropoxy)-6-methoxyquinoline-3-carbonitrile
214470-68-5
Bosutinib
6
7-(3-Chloropropoxy)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methoxyquinoline-3-carbonitrile
380844-49-5
Bosutinib
7
1-chloro-5-isopropoxy-2-methyl-4-nitrobenzene
1032903-50-6
Ceritinib (LDK378)
8
5-Methyl-2-(1-Methylethoxy)-4- (4-piperidinyl)- Benzenamine dihcl
1380575-45-0
Ceritinib (LDK378)
9
tert-butyl 4-(4-aMino-5-isopropoxy-2-Methylphenyl)piperidine-1-carboxylate
1032903-63-1
Ceritinib (LDK378)
10
2-(isopropylsulfonyl)aniline
76697-50-2
Ceritinib (LDK378)
11
2,5-dichloro-N-(2-(isopropylsulfonyl)phenyl)pyrimidin-4-amine
761440-16-8
Ceritinib (LDK378)
12
5-Formyl-2-Furanylboronic Acid
27329-70-0
Lapatinib
13
N-[3-Chloro-4-(3-fluorobenzyloxy)-phenyl]-6-iodoquinazolin-4-amine
231278-20-9
Lapatinib
14
5-[4-[[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-6-quinazolinyl]-2-Furancarboxaldehyde
231278-84-5
Lapatinib
15
Lapatinib base
231277-92-2
Lapatinib
16
(R)-2-(2,5-Difluorophenyl)pyrrolidine Hcl
1218935-60-4
Larotrectinib
17
5-chloro-3-nitropyrazolo[1,5-a]pyrimidine
1363380-51-1
Larotrectinib
18
(R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-amine
1223404-88-3
Larotrectinib
19
Larotrectinib base
1223403-58-4
Larotrectinib
20
3-(4-bromophenyl)-piperidine
769944-72-1
(MK4827) Niraparib HCl
44 Records
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